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Albert Maguire

Dr. Albert Maguire

Professor of Ophthalmology; member, Vitreo-Retinal Service; Principal Investigator of LCA-RPE65 clinical trials at the Children's Hospital of Philadelphia

Albert Maguire, MD, is a Professor of Ophthalmology at the Scheie Eye Institute at University of Pennsylvania’s School of Medicine. He is a senior member of the Retina Service at the Scheie Eye Institute and is the retina specialist at the Department of Pediatric Ophthalmology at the Children’s Hospital of Philadelphia (CHOP). Dr. Maguire has had a long-standing interest in retinal gene transfer/gene therapy and developed surgical approaches with which to deliver genes in proof-of-concept studies involving gene therapy. He has trained numerous investigators at dozens of institutions nationally and internationally on technical aspects of these procedures and has extensive experience performing subretinal injections of viral vectors. Dr. Maguire has participated in numerous clinical trials for retinal diseases. His research, conducted at Penn over the past 24 years, has resulted in approval and implementation of gene therapy clinical trials in the United States for Leber Congenital Amaurosis, including the first to enroll children for a non-lethal disease and the only current Phase 3 gene therapy clinical trial in the world. In his spare time, Dr. Maguire enjoys oil painting (typically cows and farm scenes), running, reading text books on topics ranging from geology to animal behavior, and observing his honeybees and finches.